Audible clicks from Focusrite Scarlett 2i2 3rd gen.

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in the JamKazam client, from the Manage menu:

Audio Settings/Audio Booster:
Music Bitrate - typically Auto Throttle, but you have 4 different manual settings. I use 320kb/s
Network Packet Rate - also Auto, then 3 manual choices. I use 400packets/sec
If you are in a session, such as a test session, you will be able to set your Audio Framesize. If you are not in a session you will see this value is blank. I'm running @ 1ms now, and thus far it's been stable for me. My Jam partner uses 2.5. We usually have a very good connection

Thanks so much; I'll try that tomorrow. Can you tell me if it matters whether you both have the same bitrate and packet rate, or whether resend matches those settings for you?

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resync not resend