Focusrite direct monitor question

[drux53]

I know that direct monitoring should be off when using Jamkazam, but I'm using a 10+ year old Focusrite Saffire pro 40 and there is no button to turn off the direct monitor function. Does anyone have any thoughts on how this should be set up to optimize performance and not have direct monitoring. I'm asking on this forum because the unit is old enough that it is not supported by Focusrite.
Thanks,
Michael